CD61/Integrin '3/Platelet Glycoprotein IIIa (Platelet Marker)

CD61/Integrin '3/Platelet Glycoprotein IIIa (Platelet Marker) is available at Gentaur for Next Week Delivery.

Product Short Name:  CD61/Integrin '3/Platelet Glycoprotein IIIa

Other Names: [integrin beta-3; Integrin beta-3; integrin beta-3; integrin subunit beta 3; Platelet membrane glycoprotein IIIa]

Product Gene Name: [ITGB3]

Other Gene Names: [ITGB3; ITGB3; GT; CD61; GP3A; BDPLT2; GPIIIa; BDPLT16; GP3A; GPIIIa]

Clonality:

Isotype: IgG1, kappa

Clone: [rITGB3/2145]

Host: Mouse

Reactivity: Human

Specifity: Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). It associates with the V-chain (CD51) to form vitronectin receptor, or with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61).The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.

Purity:  Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: 

Storage Stability:  Antibody with azide: store at 2 to 8°C.
Antibody without azide: store at -20 to -80°C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application:  Immunohistochemistry (IHC) Paraffin