Mybiosource
CD209/DC-SIGN (Pathogen Receptor on Dendritic Cells)
- SKU:
- MBS4380977
- Availability:
- Next week
Description
CD209/DC-SIGN (Pathogen Receptor on Dendritic Cells) is available at Gentaur for Next Week Delivery.
Product Short Name: CD209/DC-SIGN
Other Names: [DC-SIGN; CD209 antigen; CD209 antigen; CD209 molecule; C-type lectin domain family 4 member L; Dendritic cell-specific ICAM-3-grabbing non-integrin 1]
Product Gene Name: [CD209]
Other Gene Names: [CD209; CD209; CDSIGN; CLEC4L; DC-SIGN; DC-SIGN1; CLEC4L; DC-SIGN; DC-SIGN1]
Clonality:
Isotype: IgG1, kappa
Clone: [rC209/1781]
Host: Mouse
Reactivity: Human
Specifity: DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.
Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration:
Storage Stability: Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Tested Application: Immunohistochemistry (IHC) Paraffin