Caspase-14 Antibody

Caspase-14 Antibodyis available at Gentaur for Next week Delivery.

Description: Caspases are a family of cysteine proteases that play an essential role in carrying out apoptosis. Caspase-14, also named MICE, is a unique member of the caspase family with restricted expression; it is found in embryonic tissues and adult skin. Caspase-14 is weakly processed into p18 and p11 subunits by caspase-8. Caspase-14 may not play a role in apoptosis, but instead may regulate keratinocyte differentiation. Expression of caspase-14 may protect from psoriasis and irradiation damage. Caspase-14 may also be responsible for proteolytic processing of filaggrin during terminal differentiation of keratinocytes.

Immunogen Sequence:Synthetic peptide corresponding sequence surrounding amino acid 176 of human Caspase-14

Target Alternative Name:CASP-14

Species Reactivities:Human

Tag Line:Polyclonal antibody to detect Caspase-14 in human samples

Formulation:30 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2

Purification: Affinity purified

Application:Western blot

Positive Control:Jurkat cell lysate

Application And Usages:Western blot (1:100)

Handling:The antibody solution should be gently mixed before use.