c-Jun Antibody

c-Jun Antibodyis available at Gentaur for Next week Delivery.

Description: Extracellular stimuli such as growth factors and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation at Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways. JNK (c-Jun N-terminal Kinase) binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. The activity of JNK is stimulated by the same signals that activate c-Jun.

Immunogen Sequence:Recombinant human c-Jun (1-79)-GST fution protein

Target Alternative Name:JUN , AP1 , p39 , c-Jun

Species Reactivities:Human, mouse, rat

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Formulation:100 µg (0.5 mg/ml) affinity purified rabbit anti-c-Jun polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunohistochemistry

Positive Control:/

Application And Usages:Western blotting (0.5-2 µg/ml) and Immunohistochemistry (20-40 µg/ml). However, the optimal conditions should be determined individually. The antibody only recognizes c-Jun, and will not detect the endogenous levels of Jun B or Jun D.

Handling:The antibody solution should be gently mixed before use.