Description
APPBP1 Antibodyis available at Gentaur for next week delivery.
Specificity: 8883
Alternative Names:
Immunogen: A synthesized peptide derived from human APPBP1.
Technical Notes: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation.
Application: WB
Restriction:
Comments: Ice packs
Additional Information
Species Reactivity: |
Human,Mouse,Rat |
Size: |
100ug |
Host: |
Rabbit |
Clonality: |
Polyclonal |
Concentration: |
APPBP1 |
Storage: |
1mg/ml |
Expiry Date: |
-20°C |
Shipping Condition: |
1 year |
Uniprot: |
Q13564 |
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