VEGF-B Antibody

VEGF-B Antibodyis available at Gentaur for Next week Delivery.

Description: VEGF-B, a member of the VEGF family, is a potent growth and angiogenic cytokine. It promotes DNA synthesis in endothelial cells, regulates angiogenesis and vascular permeability, and inhibits apoptosis in certain smooth muscle cells and neurons. VEGF-B is expressed in all tissues except the liver. It forms cell surfaced-associated disulfide linked homodimers and can form heterodimers with VEGF-A. There are two known isoforms, formed by alternative splicing, which have been designated VEGF-B167 and VEGF-B186. Both forms have identical amino-terminal sequences encoding a “cysteine knot” like structural motif, but differ in their carboxyl-terminal domains. Both VEGF-B isoforms signal only throμgh the VEGFR1 receptor. Recombinant human VEGF-B is a 38.0 kDa disulfide-linked homodimeric protein consisting of two 167 amino acid polypeptide chains.

Immunogen Sequence:E. coli-expressed recombinant human VEGF-B

Target Alternative Name:Vascular endothelial growth factor B, VEGF-B, VEGF-related factor, VRF

Species Reactivities:Human

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Formulation:30 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

Positive Control:Recombinant human VEGF-B (Cat.# 4642-20)

Application And Usages:Western Blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant human VEGF-B (Cat.# 4642-20) can be used as a positive control.

Handling:The antibody solution should be gently mixed before use.