VDAC/Porin Antibody

VDAC/Porin Antibodyis available at Gentaur for Next week Delivery.

Description: The Voltage-Dependent Anion Channel (VDAC or mitochondrial Porin)I is an outer membrane mitochondrial protein. The VDAC protein is thoμght to form the major pores throμgh which adenine nucleotides are transferred throμgh the outer mitochondrial membrane. VDAC has also been implicated in the formation of the mitochondrial permeability transition pore complex in apoptotic cells. This complex, formed by VDAC, ANT, and CypD is thoμght to allow the mitochondria to undergo metabolic uncoupling and irreversible morphologic changes that ultimately destroy the mitochondria during apoptosis.

Immunogen Sequence:Synthetic peptide surrounding amino acid 189 of human VDAC

Target Alternative Name:VDAC1, VDAC-1 , mgC111064 , hVDAC1, Porin

Species Reactivities:Human, mouse, rat, bovine, rabbit

Tag Line:/

Formulation:30 µg (0.5 mg/ml) affinity purified rabbit anti-VDAC/Porin polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunohistochemistry

Positive Control:Western Blot: 3T3 cell lysate. IHC: Liver tissue

Application And Usages:Western blotting (0.5-4 µg/ml) and Immunohistochemistry (2.5 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~31 kDa VDAC/Porin from samples of human, mouse, rat, bovine, pig, and rabbit origins.

Handling:The antibody solution should be gently mixed before use.