VCAM-1/CD106 Antibody (Center)

VCAM-1/CD106 Antibody (Center)is available at Gentaur for Next week Delivery.

Description: Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors including neuroblastoma, rhabdomyosarcoma, Wilms’ tumors, Ewing’s sarcomas and some primitive myeloid malignancies. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily and recognizes the B2å1 and B2åM integrins. PECAM-1 (platelet/endothelial cell adhesion molecule-1), also referred to as CD31, is a glycoprotein expressed on the cell surfaces of monocytes, neutrophils, platelets and a subpopulation of T cells. VCAM-1 (vascular cell adhesion molecule-1) was first identified as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) and lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM) -like protein and is deleted in 66% of patients with Kallmann's syndrome, anosmia with secondary hypogonadism.

Immunogen Sequence:This CD106 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-322 amino acids from the Central region of human CD106.

Target Alternative Name:VCAM1; L1CAM; Vascular cell adhesion protein 1; INCAM-100

Species Reactivities:Human, Mouse.

Tag Line:Polyclonal Antibody to detect VCAM1 in human and mouse samples.

Formulation:In PBS with 0.09% (W/V) sodium azide.

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Application:Western blot.

Positive Control:Western blot: NIH-3T3 and HepG2 cell lysates.

Application And Usages:WB: 1:1000.

Handling:The antibody solution should be gently mixed before use.