USP34 Core Antibody

USP34 Core Antibodyis available at Gentaur for Next week Delivery.

Description: USP34 Core is a ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. It acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. It recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. It is involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins. Its catalytic core consists of residues 1892-2241.

Immunogen Sequence:Recombinant full length protein

Target Alternative Name:FLJ43910, KIAA0570, KIAA0729, Ubiquitin Specific Protease 34 core domain.

Species Reactivities:Human

Tag Line:Polyclonal antibody to detect USP34 Core (a DUB enzyme) in human samples.

Formulation:50 µg of antibody in PBS containing 10% glycerol

Purification: Purified from egg yolk

Application:Western blot

Positive Control:N/A

Application And Usages:Western blot: Robust detection of 100 ng of recombinant protein was possible when antibody was used at a final concentration of 5 μg/mL

Handling:The antibody solution should be gently mixed before use.