Uroplakin III Antibody

Uroplakin III Antibodyis available at Gentaur for Next week Delivery.

Description: Uroplakin IIIa is a component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. It may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence. Defects in UPK3A are a cause of renal adysplasia (RADYS) also known as renal agenesis or renal aplasia. Renal agenesis refers to the absence of one (unilateral) or both (bilateral) kidneys at birth. Bilateral renal agenesis belongs to a group of perinatally lethal renal diseases, including severe bilateral renal dysplasia, unilateral renal agenesis with contralateral dysplasia and severe obstructive uropathy.

Immunogen Sequence:Synthetic peptide at C-terminal

Target Alternative Name:Uroplakin-3a, UPK IIIa

Species Reactivities:Human, mouse, rat

Tag Line:Polyclonal Antibody to detect Uroplakin III in human, mouse and rat samples

Formulation:30 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2

Purification: Affinity purified

Application:Western blot

Positive Control:Western blot: Jurkat cell lysate

Application And Usages:Western blot: 1:200

Handling:The antibody solution should be gently mixed before use.