TrkA Antibody

TrkA Antibodyis available at Gentaur for Next week Delivery.

Description: TrkA, the high affinity Nerve Growth Factor (NGF) receptor, autophosphorylates on tyrosine to activate multiple effectors. Phosphorylation at Tyr490 is required for Shc association and activation of the Ras-MAP kinase cascade. Residues Tyr674/675 lie within the catalytic domain, and phosphorylation at these sites reflects Trk kinase activity.

Immunogen Sequence:Synthetic peptide surrounding amino acid 494 of human TrkA

Target Alternative Name:Trk-A, TRK1 , NTRK1, TRK, CIPA

Species Reactivities:Human, mouse, rat

Tag Line:/

Formulation:30 µg (0.5 mg/ml) affinity purified rabbit anti-TrkA polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunoprecipitation, Immunohistochemistry

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml) in immunoprecipitation, and Immunohistochemistry. However, the optimal conditions should be determined individually. The antibody detects ~140 kDa TrkA. It does not cross-react with TrkB or TrkC.

Handling:The antibody solution should be gently mixed before use.