TPX2 Antibody

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SKU:
3755-100
$243
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Description

TPX2 Antibodyis available at Gentaur for Next week Delivery.

Description: TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubule-dependent manner by stimulating the phosphorylation and kinase activity of Eg2. TPX2 is inactivated by binding to importin a, a nuclear import factor. Finally, the suppression of TPX2 with RNA interference causes defects in microtubule organization during mitosis.

Immunogen Sequence:Synthetic peptide from human TPX2

Target Alternative Name:TPX2, TPX-2, Microtubule-associated protein TPX2 homolog, DIL2, DIL-2, Differentially expressed in lung cells, HCA519, Hepatocellular carcinoma-associated antigen 519, REPP86, Restricted expression proliferatio

Species Reactivities:Human

Tag Line:/

Formulation:100 µl purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunoprecipitation

Positive Control:/

Application And Usages:Western blotting (1:500 – 1:2000) and Immunoprecipitation. However, the optimal concentrations should be determined individually. The antibody recognizes the human TPX2. Reactivity to other species has not been tested.

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
100 µl
Antibody Target:
TPX2
Category:
TPX
Lot Number:
51055
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
Q9ULW0
Gene Id:
22974
Concentration:
N/A
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
China
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Not Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
FACS Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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