TDRD4 Antibody

TDRD4 Antibodyis available at Gentaur for Next week Delivery.

Description: Tudor domains are small protein structural motifs of about ~50 amino acids related to the “royal family” of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The Tudor domains recognize symmetric methylated arginine or methylated lysine residues. Tudor domain proteins act as an oncogene and play a very important role in HCC and colon cancer. TDRD is also involved in RISC complex and interacts with AEG-1 oncogene. The Tudor domain can bind to methylated arginine protein and promote tumor angiogenesis in human hepatocellular carcinoma, etc. TDRD4 is a candidate CT antigen expressed in a subset of liver cancers

Immunogen Sequence:Recombinant human TDRD4 (Cat # 7251)

Target Alternative Name:RING finger protein 17, Tudor domain-containing protein 4, TDRD4, RNF17

Species Reactivities:Human

Tag Line:Polyclonal Antibody to detect TDRD4 in human samples

Formulation:30 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.

Purification: Affinity Purified Antibody

Application:Western blot

Positive Control:Western Blot: Recombinant protein

Application And Usages:Western blot: 1-4 µg/ml.

Handling:The antibody solution should be gently mixed before use.