TCR beta Antibody

TCR beta Antibodyis available at Gentaur for Next week Delivery.

Description: TCR (T cell antigen receptor) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. TCR is a heterodimer composed of either α and β or γ and δ chains. The vast majority of circulating T cells (95%) express the α/β heterodimer while roμghly 2-5% express the γ/δ heterodimer. CD3 chains and the CD4 or CD8 coreceptors are also required for efficient signal transduction throμgh the TCR.

Immunogen Sequence:Synthetic peptide surrounding amino acid 114 of human TCR-β

Target Alternative Name:T cell antigen receptor, T cell receptor beta, TCRB, TRB

Species Reactivities:Human, mouse, rat

Tag Line:/

Formulation:In PBS pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% Proclin.

Purification: Affinity purified

Application:Western blot, Immunoprecipitation, Immunohistochemistry

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml). Based on researcher’s feedback, the antibody can also be used in immunoprecipitation (10-20 µg/ml); and Immunohistochemistry (15-25 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes multiple TCR-beta forms including 17 kDa monomer, 34 kDa dimer and the 68 kDa precursor forms. Jurkat cell lysate can be used as a positive control.

Handling:The antibody solution should be gently mixed before use.