Sushi Antibody

Sushi Antibodyis available at Gentaur for Next week Delivery.

Description: Sushi Peptide S3 is a trimer of one of the high endotoxin-binding domains, Sushi 3 (or S3) within Factor C, a lipopolysaccharide (LPS)-sensitive serine protease of the horseshoe crab (Limulus Polyphemus). S3 display detergent-like properties in disrupting LPS aggregates, with specificity for palmitoyl-oleoyl-phosphatidylglycerol (POPG) resulting from electrostatic and hydrophobic forces between the peptides and the bacterial lipids. The unsaturated nature of POPG confers fluidity and enhances insertion of the peptides into the lipid bilayer, causing maximal disruption of the bacterial membrane. In short, peptide S3 can bind to lipopolysaccharide (LPS) and inhibit the growth of Gram-negative bacteria without affecting mammalian cells. It has been shown that endotoxin activates Factor C based catalytic coagulation cascade resulting in the gelation of Limulus blood. This process is the basis of Limulus Amebocyte Lysate (LAL) endotoxin detection method.

Immunogen Sequence:Sushi domain in from E. coli

Target Alternative Name:Factor C Sushi 3 antibody, Sushi 3 antibody

Species Reactivities:All

Tag Line:Purified Sushi polyclonal Antibody

Formulation:30 µg (0.5 mg/ml) polyclonal antibody in PBS pH 7.2, containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.

Purification: Affinity purified

Application:Western Blot

Positive Control:Recombinant Sushi protein

Application And Usages:Western Blot analysis (1-4 µg/ml).

Handling:The antibody solution should be gently mixed before use.