Sox-2 Antibody (Clone # 57CT23.3.4)

Sox-2 Antibody (Clone # 57CT23.3.4)is available at Gentaur for Next week Delivery.

Description: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the H mg-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes clusters at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Immunogen Sequence:SOX2 recombinant protein is used to produce this monoclonal antibody.

Target Alternative Name:SOX2; Transcription factor SOX-2

Species Reactivities:Human.

Tag Line:Monoclonal Antibody to detect Sox-2 in human samples.

Formulation:This antibody is purified through a protein G column, followed by dialysis against PBS.

Purification: N/A

Application:Western blot, IHC, FACS, IF.

Positive Control:Western blot: SOX-2 protein, IHC: human lung carcinoma, FACS: NCI-H460 cells, IF: A549 and SY5S cells.

Application And Usages:Western blot: ~1:200 – 1:2000, IHC: 1:50 – 1:100, FACS: 1:10 – 1:50, IF: 1:100.

Handling:The antibody solution should be gently mixed before use.