SHH Polyclonal Antibody

SHH Polyclonal Antibodyis available at Gentaur for Next week Delivery.

Description: Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO.

Immunogen Sequence:mouse recombinant SHH (Cat. No. 4020)

Target Alternative Name:Sonic hedgehog protein, HHG-1, SHH

Species Reactivities:Human, Mouse

Tag Line:Polyclonal Antibody to detect SHH in Human, Mouse samples

Formulation:100 µg (0.5 mg/ml) of antibody in PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin®, and 50 % glycerol.

Purification: Affinity purified rabbit IgG

Application:Western blot

Positive Control:Western blot

Application And Usages:Western blot: 1-4 µg/ml

Handling:The antibody solution should be gently mixed before use.