RIP3 Antibody

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SKU:
3293-30T
  • RIP3 Antibody
  • RIP3 Antibody
$88
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Description

RIP3 Antibodyis available at Gentaur for Next week Delivery.

Description: Receptor interacting protein including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3. RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the c-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, and mediates TNF-R1 mediated apoptosis, and attenuates RIP and TNFR1 induced NFkB activation. Overexpression of RIP3 induces apoptosis and NFkB activation.

Immunogen Sequence:Synthetic peptide corresponding to residues surrounding amino acid 476 of mouse RIP3

Target Alternative Name:RIP like protein kinase 3, RIPK3, RIPK3

Species Reactivities:Mouse, rat

Tag Line:/

Formulation:In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin

Purification: Affinity purified

Application:Western blot, Immunohistochemistry

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml) and in Immunohistochemistry (10-20 µg/ml). Rat kidney tissue section can be used as a positive control. An approximately 57 kDa band should be detected.

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
30 µg
Antibody Target:
RIP3
Category:
RIP
Lot Number:
51093
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
NP_001157580
Gene Id:
56532
Concentration:
0.5 mg/ml
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
China
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Not Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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