RARA polyclonal antibody

RARA polyclonal antibodyis available at Gentaur for Next week Delivery.

Description: RARA is a receptor for retinoic acid, a vitamin A metabolite, which directly regulates gene expression in target cells by binding to specific DNA response elements. In the absence of its ligand, this receptor represses transcription through the recruitment of specific corepressors and of HDAC’s, whereas binding of retinoic acid causes the recruitment of coactivators and HAT’s. Translocations involving the RARA gene, often leading to a RARA/PML fusion protein, are a major cause of acute promyelocytic leukemia.

Immunogen Sequence:Human RARA (Retinoic Acid Receptor alpha) using two KLH-conjugated synthetic peptides containing sequences from the C-terminal region of the protein.

Target Alternative Name:Retinoic acid receptor alpha, Nuclear receptor subfamily 1 group B member 1, NR1B1

Species Reactivities:Human.

Tag Line:Polyclonal Antibody to detect RARA in human samples.

Formulation:In PBS with 0.05% (W/V) sodium azide.

Purification: Whole Anti-Sera

Application:Western blot, ELISA, ChIP.

Positive Control:Western blot: Human embryonic kidney cells, ELISA: peptides, ChIP: NB4 cells.

Application And Usages:ChIP: 4 µg/ChIP, WB: 1:750, ELISA: 1:50.

Handling:The antibody solution should be gently mixed before use.