PI-8 Antibody

PI-8 Antibodyis available at Gentaur for Next week Delivery.

Description: High molecular weight serine protease inhibitors (serpins) are large superfamily of proteins, which bind to and inactivate serine proteinases. In 1995 Sprecher et al. cloned 2 novel serpins, termed PI8 and PI9, from human placenta cDNA library. Sequencing showed that PI8 encodes 376-amino acids. PI8 are localized to the cytoplasm of transfected cells and was able to form an SDS- complex. PI8 is implicated to inhibit furin enzymatic activity and plays a role in platelet-regulated pathophysiological responses.

Immunogen Sequence:Synthetic peptide surrounding amino acid 10 of human PI-8

Target Alternative Name:CAP2 , PI8 , SERPINB8

Species Reactivities:Human

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Formulation:0.5 mg/ml purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 1% BSA, 30% glycerol and 0.02% thimerosal.

Purification: Affinity purified

Application:Western blot

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Application And Usages:Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 40-45 kDa human PI-8. Reactivity to other species has not been tested.

Handling:The antibody solution should be gently mixed before use.