Phospho-VASP Antibody

Phospho-VASP Antibodyis available at Gentaur for Next week Delivery.

Description: Vasodilator-stimulated phosphoprotein (VASP) belongs to the Ena/VASP family of adaptor proteins linking the cytoskeletal system to the signal transduction pathways. VASP functions in cytoskeletal organization, fibroblast migration, platelet activation and axon guidance. Three phosphorylation sites, Ser157, Ser239 and Thr278, have been identified. Ser157 is the major PKA phosphorylation site. Evidence sμggests that VASP phosphorylation reduces its association with actin and has a negative effect on actin polymerization.

Immunogen Sequence:Synthetic phospho peptide surrounding amino acid Ser157 of human VASP

Target Alternative Name:Vasodilator-stimulated phosphoprotein

Species Reactivities:Human, mouse, rat

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Formulation:100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in 1X phosphate-buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

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Application And Usages:Western blotting (0.5-4 µg/ml) and Immunohistochemistry. However, the optimal concentrations should be determined individually. The antibody recognizes 51 kDa phosphorylated VASP from samples of human, mouse, and rat origins. Reactivity to other species has not been tested.

Handling:The antibody solution should be gently mixed before use.