Phospho TGFBR2 (Ser225) Antibody

Phospho TGFBR2 (Ser225) Antibodyis available at Gentaur for Next week Delivery.

Description: The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Immunogen Sequence:KLH-conjugated synthetic peptide targeting a sequence within the center region of human TGFBR2

Target Alternative Name:TGF-beta receptor type-2; TGFR-2; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TbetaR-II

Species Reactivities:Porcine, Rat, Rabbit, Mouse, Human

Tag Line:Affinity purified rabbit polyclonal antibody to detect phosphorylation of TGFBR2 at Ser225 in human, mouse, rat, porcine, rabbit samples

Formulation:In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application:Western Blotting

Positive Control:/

Application And Usages:WB 1:500 - 1:1000

Handling:The antibody solution should be gently mixed before use.