Phospho-Tau Antibody

Phospho-Tau Antibodyis available at Gentaur for Next week Delivery.

Description: Tau, a microtubule-binding protein which serves to stabilize microtubules in growing axons, is found to be hyperphosphorylated in paired helical filaments (PHF), the major fibrous component of neurofibrillary lesions associated with Alzheimer’s disease. Hyperphosphorylation of Tau is thoμght to be the critical event leading to the assembly of PHF. Six Tau protein isoforms have been identified, all of which are phosphorylated by GSK3. This presents the possibility that miscues in GSK3 signaling contribute to the onset of Alzheimer’s disease.

Immunogen Sequence:N/A

Target Alternative Name:MAPT; DDPAC; FLJ31424; FTDP-17; MAPTL; mgC138549; MSTD; MTBT1; MTBT2; PPND; TAU

Species Reactivities:Human, mouse, rat

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Formulation:100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blotting (1:500-2000). However, the optimal concentrations should be determined individually.

Handling:The antibody solution should be gently mixed before use.