Phospho SMAD3 (Ser425) Antibody

Phospho SMAD3 (Ser425) Antibodyis available at Gentaur for Next week Delivery.

Description: The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. It also functions as a tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3.

Immunogen Sequence:KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human SMAD3

Target Alternative Name:MADH3; Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3

Species Reactivities:Chicken, Human

Tag Line:Affinity purified rabbit polyclonal antibody to detect phosphorylation of SMAD3 at Ser425 in human and chicken samples

Formulation:In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application:Immunohistochemistry (IHC), Western Blotting

Positive Control:/

Application And Usages:WB 1:500 - 1:1000, IHC 1:100 - 1:200

Handling:The antibody solution should be gently mixed before use.