Phospho PFKFB2 (Ser483) Antibody

Phospho PFKFB2 (Ser483) Antibodyis available at Gentaur for Next week Delivery.

Description: The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.

Immunogen Sequence:KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human PFKFB2.

Target Alternative Name:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6PF-2-K/Fru-2,6-P2ase 2; PFK/FBPase 2; 6PF-2-K/Fru-2,6-P2ase heart-type isozyme

Species Reactivities:Bovine, Rat, Mouse, Human

Tag Line:Affinity purified rabbit polyclonal antibody to detect phosphorylation of PFKFB2 at Ser483 in human, mouse, rat and bovine samples

Formulation:In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application:Western Blotting

Positive Control:/

Application And Usages:WB 1:500 - 1:1000

Handling:The antibody solution should be gently mixed before use.