Phospho PDGFR-beta (Tyr751) Antibody

Phospho PDGFR-beta (Tyr751) Antibodyis available at Gentaur for Next week Delivery.

Description: The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia.

Immunogen Sequence:KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PDGFR beta

Target Alternative Name:PDGFR; PDGFR1; Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-derived growth factor receptor 1; PDGFR-1; CD140b

Species Reactivities:Bovine, Porcine, Dog, Rabbit, Rat, Mouse, Human

Tag Line:Affinity purified rabbit polyclonal antibody to detect phosphorylation of PDGFRB at Tyr751 in human, mouse, rat, bovine, dog, porcine and rabbit samples

Formulation:In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application:Western Blotting

Positive Control:/

Application And Usages:WB 1:500 - 1:1000

Handling:The antibody solution should be gently mixed before use.