Phospho PAK4 (Ser474) Antibody

Phospho PAK4 (Ser474) Antibodyis available at Gentaur for Next week Delivery.

Description: PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Immunogen Sequence:KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human PAK4.

Target Alternative Name:KIAA1142; Serine/threonine-protein kinase PAK 4; p21-activated kinase 4; PAK-4

Species Reactivities:Bovine, Rat, Mouse, Human

Tag Line:Affinity purified rabbit polyclonal antibody to detect phosphorylation of PAK4 at Ser474 in human, mouse, rat and bovine samples

Formulation:In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application:Immunofluorescence (IF), Western Blotting

Positive Control:/

Application And Usages:WB 1:500 - 1:1000, IF 1:100 - 1:500

Handling:The antibody solution should be gently mixed before use.