Phospho NMDAR2B (Tyr1474) Antibody

Phospho NMDAR2B (Tyr1474) Antibodyis available at Gentaur for Next week Delivery.

Description: This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia.

Immunogen Sequence:KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human NMDAR2B

Target Alternative Name:Glutamate receptor ionotropic, NMDA 2B, GluN2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, NR2B, N-methyl-D-aspartate receptor subunit 3, NR3, hNR3, MRD6, EIEE27, GRIN2B

Species Reactivities:Dog,Rat,Mouse,Human

Tag Line:Rabbit polyclonal antibody to detect phosphorylation of NMDAR2B at Tyr1474 in human, mouse, rat and dog samples

Formulation:In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application:Western Blotting

Positive Control:/

Application And Usages:WB (1:500 - 1:1000)

Handling:The antibody solution should be gently mixed before use.