Phospho-LCK (Tyr394) Monoclonal Antibody

Phospho-LCK (Tyr394) Monoclonal Antibodyis available at Gentaur for Next week Delivery.

Description: Lck is a membrane associated tyrosine protein kinases. The Lck gene has been shown to undergo rearrangement and overexpression in some murine lymphomas. In human studies, it has been demonstrated that the Lck gene is localized to a site in the genome which undergoes frequent chromosomal abnormalities in lymphomas and neuroblastomas. Resting T cells contain high levels of the Lck protein and mRNA both of which decline upon activation of the T cells. These and other observations sμggest that alterations in Lck expression may contribute to the pathogenesis of some types of neoplastic disease.

Immunogen Sequence:/

Target Alternative Name:LCK , p56-LCK , p56lck , YT16 , pp58lck , LSK

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect Lck (Phospho-Tyr394) in human samples.

Formulation:100 ug (1 mg/ml) of antibody in 0.01M Tris-HCl, pH 8.0, 0.15M NaCl, and 0.02% sodium azide.

Purification: Affinity purified mouse IgG using protein G

Application:Western blot, Immunoprecipitation, ELISA

Positive Control:N/A

Application And Usages:N/A

Handling:The antibody solution should be gently mixed before use.