Phospho Histone H2AX (Ser139) Antibody

Phospho Histone H2AX (Ser139) Antibodyis available at Gentaur for Next week Delivery.

Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Immunogen Sequence:KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human Histone H2AX

Target Alternative Name:H2AX; Histone H2AX; H2a/x; Histone H2A.X

Species Reactivities:Rabbit, Mouse, Human

Tag Line:Affinity purified rabbit polyclonal antibody to detect phosphorylation of Histone H2AX at Ser139 in human, mouse and rabbit samples

Formulation:In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application:Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting, Flow Cytometry

Positive Control:/

Application And Usages:WB 1:500 - 1:1000, IHC 1:100 - 1:200, IP 1:10 - 1:100, FC 1:100 - 1:200

Handling:The antibody solution should be gently mixed before use.