Phospho-GSK-3b Antibody

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SKU:
3495-100
$342
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Description

Phospho-GSK-3b Antibodyis available at Gentaur for Next week Delivery.

Description: Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase that has been implicated in the regulation of cell fate and in the Wnt signaling pathway. GSK-3 plays an important role in the PI3 kinase and Akt mediated cell survival pathways, and its activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3α and Ser9 of GSK-3β. GSK-3 has also been implicated in alzheimer’s disease. Six Tau protein isoforms have been identified, all of which are phosphorylated by GSK-3.

Immunogen Sequence:Synthetic peptide surrounding Ser9 of human GSK-3β

Target Alternative Name:EC 2.7.11.26, GSK-3beta , glycogen synthase kinase 3 beta

Species Reactivities:Human, mouse, rat

Tag Line:/

Formulation:100 µg (0.5 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunohistochemistry

Positive Control:/

Application And Usages:Western blot analysis (1-2 µg/ml) and Immunohistochemistry (15-30 µg/ml). However, the optimal conditions should be determined individually. The antibody detects phosphorylated GSK-3β (Ser9) in samples from human, mouse, and rat origin. It does not recognize the phosphorylated GSK-3α.

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
100 µg
Antibody Target:
Phospho-GSK-3b
Category:
GSK
Lot Number:
51295
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
NP_002084
Gene Id:
2932
Concentration:
0.5 mg/ml
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
China
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Not Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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