Phospho-Elk-1 Antibody

Phospho-Elk-1 Antibodyis available at Gentaur for Next week Delivery.

Description: Elk-1 is a transcription factor that binds the serum response element (SRE) and mediates gene activity in response to serum and growth factors. Elk-1 is phosphorylated by MAP kinase pathways and appears to be a direct target of activated MAP kinase. Biochemical studies indicate that Elk-1 is a good substrate for MAP kinase. The kinetics of Elk-1 phosphorylation and activation correlate with MAP kinase activity. Other studies have shown that Elk-1 (Ser383) is also a target of the stress-activated kinase SAPK/JNK.

Immunogen Sequence:Synthetic peptide surrounding amino acid 383 of human Elk-1

Target Alternative Name:phosphoELK1, phospho ELK 1, phospho ELK- 1, elk-1, Oncogene Elk1, ELK1 member of ETS oncogene family

Species Reactivities:Human, mouse, rat

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Formulation:100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody detects 62 kDa phosphorylated Elk-1 (Ser383) of human, mouse and rat origins.

Handling:The antibody solution should be gently mixed before use.