Phospho-DDX3X (Thr322) Antibody

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SKU:
A1155-100
£237.81
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Description

Phospho-DDX3X (Thr322) Antibodyis available at Gentaur for Next week Delivery.

Description: Multifunctional ATP-dependent RNA helicase. The ATPase activity can be stimulated by various ribo- and deoxynucleic acids indicative for a relaxed substrate specificity. In vitro can unwind partially double-stranded DNA with a preference for 5'-single-stranded DNA overhangs. Is involved in several steps of gene expression, such as transcription, mRNA maturation, mRNA export and translation. However, the exact mechanisms are not known and some functions may be specific for a subset of mRNAs. Involved in transcriptional regulation. Can enhance transcription from the CDKN1A/WAF1 promoter in a SP1-dependent manner. Found associated with the E-cadherin promoter and can down-regulate transcription from the promoter.

Immunogen Sequence:KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DDX3X

Target Alternative Name:DBX, DDX3, ATP-dependent RNA helicase DDX3X, DEAD box protein 3 X-chromosomal; DEAD box X isoform, Helicase-like protein 2, HLP2

Species Reactivities:Human

Tag Line:Polyclonal antibody to detect endogenous levels of DDX3X (pT322) in human.

Formulation:In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide

Purification: Affinity purified

Application:WB, IH, IF/IC

Positive Control:WB: HeLa cell lysates; IHC: human brain tissue; IFC HeLa cells

Application And Usages:WB; 1:500 – 1:2000, IHC; 1:50 – 1:200, IF/IC; 1:50 – 1:100

Handling:The antibody solution should be gently mixed before use

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Additional Information

Size:
100 µl
Antibody Target:
DDX3X
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
O00571
Gene Id:
1654
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20°C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Verified
Immunofluorescence Verified:
Verified
Immunoprecipitation Verified:
Not Verified
FACS Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Dot Blot Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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