Phospho-DDX3X (Thr322) Antibody

Phospho-DDX3X (Thr322) Antibodyis available at Gentaur for Next week Delivery.

Description: Multifunctional ATP-dependent RNA helicase. The ATPase activity can be stimulated by various ribo- and deoxynucleic acids indicative for a relaxed substrate specificity. In vitro can unwind partially double-stranded DNA with a preference for 5'-single-stranded DNA overhangs. Is involved in several steps of gene expression, such as transcription, mRNA maturation, mRNA export and translation. However, the exact mechanisms are not known and some functions may be specific for a subset of mRNAs. Involved in transcriptional regulation. Can enhance transcription from the CDKN1A/WAF1 promoter in a SP1-dependent manner. Found associated with the E-cadherin promoter and can down-regulate transcription from the promoter.

Immunogen Sequence:KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DDX3X

Target Alternative Name:DBX, DDX3, ATP-dependent RNA helicase DDX3X, DEAD box protein 3 X-chromosomal; DEAD box X isoform, Helicase-like protein 2, HLP2

Species Reactivities:Human

Tag Line:Polyclonal antibody to detect endogenous levels of DDX3X (pT322) in human.

Formulation:In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide

Purification: Affinity purified

Application:WB, IH, IF/IC

Positive Control:WB: HeLa cell lysates; IHC: human brain tissue; IFC HeLa cells

Application And Usages:WB; 1:500 – 1:2000, IHC; 1:50 – 1:200, IF/IC; 1:50 – 1:100

Handling:The antibody solution should be gently mixed before use