Phospho-Connexin 43 (Ser368) Antibody

Phospho-Connexin 43 (Ser368) Antibodyis available at Gentaur for Next week Delivery.

Description: Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract. May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles.

Immunogen Sequence:Synthesized peptide derived from human Connexin 43 around the phosphorylation site of S368

Target Alternative Name:Gap junction alpha-1 protein, Connexin-43, Cx43, Gap junction 43 kDa heart protein, GJA1, GJAL

Species Reactivities:Human, Mouse, Rat

Tag Line:Polyclonal antibody to detect endogenous levels of Connexin 43 (Ser368) in human, mouse and rat samples

Formulation:In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Purification: Affinity-chromatography using epitope-specific immunogen

Application:WB, IHC, ELISA

Positive Control:WB: HuvEc cell lysate

Application And Usages:WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000

Handling:The antibody solution should be gently mixed before use