Phospho-CaMKII Antibody

Phospho-CaMKII Antibodyis available at Gentaur for Next week Delivery.

Description: CaMKII is a member of calcium/calmodulin-activated kinase, functioning in neural synaptic stimulation and T-cell receptor signaling. CaMKII has catalytic and regulatory domains. The binding of Ca++/calmodulin to its regulatory domain releases its autoinhibitory effect and activates the kinase. The activated CaMKII further autophosphorylates itself at Thr286 to render the kinase constitutively active.

Immunogen Sequence:Synthetic phospho-peptide corresponding to residues surrounding Thr286 of human CaMKII

Target Alternative Name:CAMK2A ,CAMKA ,KIAA0968,EC 2.7.11.17

Species Reactivities:Human, mouse, rat

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Formulation:100 µl purified rabbit polyclonal anti-Phospho-CaMKII (Thr286) antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.

Purification: Affinity purified

Application:Western blot

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Application And Usages:Western blotting at 1-2 µg/ml. However, the optimal concentrations should be determined individually. The anti-Phospho-CaMKII antibody recognizes only the phosphorylated CaMKII (Thr286) in samples from human, mouse, and rat origins.

Handling:The antibody solution should be gently mixed before use.