Phospho-Calnexin (Ser583) Antibody

Phospho-Calnexin (Ser583) Antibodyis available at Gentaur for Next week Delivery.

Description: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.

Immunogen Sequence:Synthesized peptide derived from human Calnexin around the phosphorylation site of S583. AA- 520-600

Target Alternative Name:Calnexin, IP90, Major histocompatibility complex class I antigen-binding protein p88, p90

Species Reactivities:Human, Mouse, Rat

Tag Line:Polyclonal antibody to detect endogenous levels of Calnexin (pS583) in human, mouse and rat samples

Formulation:In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Purification: Affinity-chromatography using epitope-specific immunogen

Application:WB, ELISA, IHC, IF

Positive Control:WB: HepG2 cell lysate

Application And Usages:WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000

Handling:The antibody solution should be gently mixed before use