Phospho-AP-1 (Ser63) Antibody

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SKU:
A1249-100
$282
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Description

Phospho-AP-1 (Ser63) Antibodyis available at Gentaur for Next week Delivery.

Description: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells. Binds to the USP28 promoter in colorectal cancer (CRC) cells

Immunogen Sequence:Synthesized peptide derived from human AP-1 around the phosphorylation site of S63 (10-90aa)

Target Alternative Name:JUN; Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39

Species Reactivities:Human, mouse , rat

Tag Line:Polyclonal antibody to detect endogenous levels of AP-1 protein when phosphorylated at Ser63 in human, mouse and rat.

Formulation:In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Purification: Affinity-chromatography using epitope-specific immunogen

Application:WB, ELISA, IHC

Positive Control:WB: HeLa cell lysate

Application And Usages:WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000

Handling:The antibody solution should be gently mixed before use

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Additional Information

Size:
100 µl
Antibody Target:
JUN
Category:
Signalling
Lot Number:
N/A
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
P05412
Gene Id:
3725
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20°C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Not Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
FACS Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Dot Blot Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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