PAX6 Polyclonal Antibody

PAX6 Polyclonal Antibodyis available at Gentaur for Next week Delivery.

Description: PAX genes encode nuclear transcription factors that may function as major controllers of developmental processes in both vertebrates and invertebrates. Mutations in murine PAX genes underlie three natural mouse alleles and several corresponding human syndromes (aniridia, foveal hypoplasia and Peters’ anomaly). Murine PAX genes have been shown to be proto-oncogenes. Furthermore, human PAX genes have recently been demonstrated to play an influential part in some common human cancers such as brain tumors and lymphomas. All PAX genes encode a DNA-binding domain termed the paired domain and in addition some also encode a second binding domain--the paired type homeobox. PAX6 is involved in the early development of the optical vesicle and has been shown to interact with Six3, another important visual development protein.

Immunogen Sequence:N/A

Target Alternative Name:Oculorhombin

Species Reactivities:Human, Mouse, Rat, sheep, chicken, frog

Tag Line:Polyclonal Antibody to detect Pax6 in Human, Mouse, Rat samples

Formulation:100 mg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.

Purification: Affinity purified rabbit IgG

Application:Western blot

Positive Control:N/A

Application And Usages:Western blot: 1-4 µg

Handling:The antibody solution should be gently mixed before use.