PANX1 Antibody (NT)

PANX1 Antibody (NT)is available at Gentaur for Next week Delivery.

Description: The pannexin gene family encodes a second class of putative gap junction proteins and is highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.

Immunogen Sequence:Rabbit polyclonal PANX1 antibody was raised against a 17 amino acid peptide near the amino terminus of human PANX1.

Target Alternative Name:Pannexin 1, Pannexin-1, PX1, MRS1, UNQ2529, UNQ2529/PRO6028

Species Reactivities:Human, Mouse, Rat

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Formulation:100 µg (1 mg/ml) in 1X PBS containing 1 mg/ml BSA, 50% glycerol and less than 0.02% sodium azide, pH 7.4.

Purification: Affinity chromatography purified via peptide column

Application:Western blot, ELISA

Positive Control:Western Blot: Human Ovary tissue lysate

Application And Usages:Western Blot: 1 - 2 μg/ml, ELISA. However, the optimal conditions should be determined individually.

Handling:The antibody solution should be gently mixed before use.