OCT4 (OCT3) Antibody

OCT4 (OCT3) Antibodyis available at Gentaur for Next week Delivery.

Description: Oct-4 (POU5F1) is a transcription factor highly expressed in undifferentiated embryonic stem cells and embryonic germ cells. A network of key factors that includes Oct-4, Nanog, and Sox2 is necessary for the maintenance of pluripotent potential, and downregulation of Oct-4 has been shown to trigger cell differentiation. Research studies have demonstrated that Oct-4 is a useful germ cell tumor marker. Oct-4 exists as two splice variants, Oct-4A and Oct-4B. Recent studies have suggested that the Oct-4A isoform has the ability to confer and sustain pluripotency, while Oct-4B may exist in some somatic, non-pluripotent cells.

Immunogen Sequence:This OCT4 (OCT3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-141 amino acids from human OCT4 (OCT3).

Target Alternative Name:POU5F1; OCT3; OCT4; OTF3; POU domain, class 5, transcription factor 1; Octamer-binding protein 3; Octamer-binding protein 4; Octamer-binding transcription factor 3

Species Reactivities:Human.

Tag Line:Polyclonal Antibody to detect Oct4/Oct3 in human samples.

Formulation:Supplied in PBS with 0.09% (W/V) sodium azide.

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Application:Western blot, IF.

Positive Control:Western blot: HL-60 cell lysate, IF: Sy5Y cells

Application And Usages:Western blot: ~1:1000, IF: ~1:10–1:50.

Handling:The antibody solution should be gently mixed before use.