Oct-4 Antibody

Oct-4 Antibodyis available at Gentaur for Next week Delivery.

Description: Members of Oct family of transcription factors specifically interact with Octamer motif ATGCAAAT, a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes. All of the members of the Oct family contain two highly conserved domains which are separated by 14-26 variable amino acids. These include the POU homeodomain and the POU-specific domain. Both are required for DNA binding and are involved in protein-protein interactions. Evidences indicate that regulation of Oct family transcription factors occurs at the level of phosphorylation.

Immunogen Sequence:Synthetic peptide mapping to the N-terminus of mouse Oct-4

Target Alternative Name: mgC22487, OCT3, OTF3, OTF4, Oct4 , POU5F1 , Oct-3

Species Reactivities:Human, mouse, rat

Tag Line:/

Formulation:30 µg (0.5 mg/ml) affinity purified rabbit anti-Oct-3/4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.03% ProClin®.

Purification: Affinity purified

Application:Western blot, Immunoprecipitation, Immunohistochemistry

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml), immunoprecipitation (20 µg/ml) and Immunohistochemistry (20 µg/ml). However, the optimal conditions should be determined individually. The antibody reacts with 45 kDa Oct-4 (also designated Oct-3A) and in a less extent 33 kDa Oct-3B from human, mouse, and rat samples. Rat kidney tissue lysate can be used as a positive control.

Handling:The antibody solution should be gently mixed before use.