NATL/LAB Antibody

NATL/LAB Antibodyis available at Gentaur for Next week Delivery.

Description: Non-T cell Activation Linker (NTAL) is also known as linker for activation of B cells (LAB), is a transmembrane adaptor protein. NTAL is expressed in B cells, mast cells, monocytes and NK cells. When NTAL is tyrosine phosphorylated, it recruits signalling molecules such as Grb2, Gab2 and c-Cbl into receptor-signalling complexes. Mutation in the NTAL gene may cause Williams-Beuren syndrome, a rare genetic disorder.

Immunogen Sequence:Synthetic peptide surrounding amino acid 187 of rat NTAL

Target Alternative Name:HSPC046 , LAB , LAT2 , NTAL, WBSCR15, WBSCR5 , WSCR5

Species Reactivities:Rat

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Formulation:30 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects a 22 kDa rat NTAL/LAB. Other species have not been determined.

Handling:The antibody solution should be gently mixed before use.