MUC1 Antibody (EP1024Y)

MUC1 Antibody (EP1024Y)is available at Gentaur for Next week Delivery.

Description: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.

Immunogen Sequence:Purified His-tagged MUC1 protein (N-terminal fragment)

Target Alternative Name:Mucin-1, MUC-1, Breast carcinoma-associated antigen DF3, Cancer antigen 15-3, CA 15-3, Carcinoma-associated mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive urinary mucin, PUM, Polymorphic epithelial mucin, PEM, Tumor-associated epithelial membrane antigen, EMA, Tumor-associated mucin, CD227

Species Reactivities:Human

Tag Line:Monoclonal Antibody to detect MUC1 in Human samples.

Formulation:100 µl antibody supplied in PBS with 0.09% (W/V) sodium azide.

Purification: Affinity purified mouse IgG

Application:Western Blot

Positive Control:Western blot

Application And Usages:Western Blot 1:1000; Immunohistochemistry 1:100 - 250

Handling:The antibody solution should be gently mixed before use.