MMP-11 Antibody

MMP-11 Antibodyis available at Gentaur for Next week Delivery.

Description: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.

Immunogen Sequence:Synthetic peptide surrounding amino acid 464 of mouse MMP-11

Target Alternative Name:ST3 , SL-3 , MMP-11 , STMY3 , Matrix metalloproteinase

Species Reactivities:Human, mouse, rat

Tag Line:/

Formulation:30 µg (0.5 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunohistochemistry

Positive Control:Western Blot: Jurkat cell lysate. IHC: Adrenal tissue

Application And Usages:Western blotting (0.5-4 µg/ml) and Immunohistochemistry (5 µg/ml). However, the optimal conditions should be determined individually. Blocking peptide (3531RBP-50) is available separately. The antibody recognizes the latent form (~68 kDa) and the active forms (~55 kDa and ~40 kDa) of MMP-11 from human, mouse, and rat origins.

Handling:The antibody solution should be gently mixed before use.