Mitofusin 2 Antibody

Mitofusin 2 Antibodyis available at Gentaur for Next week Delivery.

Description: Mitofusin 2 (Mfn 2) is mostly expressed in the heart and muscle tissues. It is a transmembrane protein that mediates mitochondria fusion and plays a central role in the maintenance of mitochondrial morphology. A GTPase domain is required for the function of Mitofusin proteins. Mutations in Mfn2 can lead to Charcot-Marie-Tooth disease, a common inherited disorder of the peripheral nervous system. Mfn2 may also be associated with obesity and/or apoptosis.

Immunogen Sequence:Synthetic peptide corresponding to residues surrounding amino acid 719 of human Mitofusin 2

Target Alternative Name:mitofusin2, mitofusin 2, mitofusin-2, MFN2, CMT2A, CMT2A2, CPRP1, HSG, KIAA0214, MARF

Species Reactivities:Human, mouse, rat

Tag Line:/

Formulation:30 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 68 kDa and 86 kDa bands from samples of human, mouse, rat origins. Reactivity to other species has not been tested.

Handling:The antibody solution should be gently mixed before use.