MBP Monoclonal Antibody

MBP Monoclonal Antibodyis available at Gentaur for Next week Delivery.

Description: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.

Immunogen Sequence:/

Target Alternative Name:Myelin A1 protein, Myelin membrane encephalitogenic protein

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect Myelin basic protein in human samples.

Formulation:100 ug (1 mg/ml) of antibody in 0.01M Tris-HCl, pH 8.0, 0.15M NaCl, and 0.02% sodium azide.

Purification: Affinity purified mouse IgG using protein G

Application:WB

Positive Control:N/A

Application And Usages:Western blot

Handling:The antibody solution should be gently mixed before use.