MBD4 Antibody

MBD4 Antibodyis available at Gentaur for Next week Delivery.

Description: MBD4 (methyl-CpG-binding domain protein 4) belongs to the MBD family of nuclear proteins that bind to methylated CpG sites and represses gene transcription. Human proteins MECP2, MBD1, MBD2, and MBD4, except MBD3 bind specifically to methylated DNA. MBD4 exhibits thymine glycosylase activity and is known to play an important function in DNA mismatch repair and apoptosis.

Immunogen Sequence:Synthetic peptide surrounding amino acid 474 of mouse MBD4

Target Alternative Name:MBD4, Methyl-CpG-binding domain protein 4, Methyl-CpG-binding endonuclease 1, Methyl-CpG-binding protein, MBD4, Mismatch-specific DNA N-glycosylase, MED1

Species Reactivities:Human, mouse, rat

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Formulation:30 µg (0.5 mg/ml) affinity purified rabbit anti-MBD4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

Positive Control:Jurkat cell lysates

Application And Usages:The antibody can be used in Western Blot analysis (0.5-4 µg/ml). However, the optimal concentrations should be determined individually.

Handling:The antibody solution should be gently mixed before use.