LXR Antibody

LXR Antibodyis available at Gentaur for Next week Delivery.

Description: Liver X receptors (LXRs) are oxysterol activated nuclear receptors which are involved in the regulation of genesis and metabolism of cholesterols and bile acids. LXRs form heterodimeric complexes with the retinoic acid receptors (RARs) once activated by their respective oxysterol ligands. Two known isoforms, alpha and beta, are differentially expressed; the alpha isoform predominantly expressed in liver, whereas beta isoform expression has been shown to be ubiquitous.

Immunogen Sequence:Synthetic peptide surrounding amino acid 435 of human LXR

Target Alternative Name:LXRA , NR1H3 , Liver X receptor alpha , LXR a , Oxysterols receptor

Species Reactivities:Human, mouse, rat

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Formulation:0.5 mg/ml affinity purified rabbit anti-LXR polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Other applications have not been determined. The antibody detects 49 kDa LXR alpha and beta subunits of human, mouse, rat and bovine LXR. Cross-reactivity to other species has not been determined. Jurkat cell lysate (Cat.# 2401-100) and mouse small intestine tissue lysate (Cat.# 2601-100) can be used as positive controls.

Handling:The antibody solution should be gently mixed before use.