KDM1B polyclonal antibody

KDM1B polyclonal antibodyis available at Gentaur for Next week Delivery.

Description: KDM1B is a histone demethylase that demethylates lysine 4 of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. KDM1B is able to demethylate both mono- and di-methylated lysine 4 of histone H3, but has no effect on tri-methylated lysine 4, mono-, di- or tri-methylated lysine 9, mono-, di- or tri-methylated lysine 27, mono-, di- or tri-methylated lysine 36 of histone H3, or on mono-, di- or tri-methylated lysine 20 of histone H4. KDM1B is also required for de novo DNA methylation of a subset of imprinted genes during oogenesis. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed.

Immunogen Sequence:Polyclonal antibody raised in rabbit against human KDM1B (lysine (K)-specific demethylase 1B) using two KLH conjugated synthetic peptides containing a sequence from the N-terminal and the central region of the protein, respectively.

Target Alternative Name:AOF1, LSD2, C6orf193

Species Reactivities:Human.

Tag Line:Polyclonal Antibody to detect KDM1B in human samples.

Formulation:In PBS with 0.05% (W/V) sodium azide.

Purification: Whole Anti-Sera

Application:ELISA.

Positive Control:ELISA: Peptides.

Application And Usages:ELISA: 1:500.

Handling:The antibody solution should be gently mixed before use.