KAP-1 Antibody

KAP-1 Antibodyis available at Gentaur for Next week Delivery.

Description: KAP-1 (KRAB-Associated Protein 1) is a member of the tripartite motif RBCC/Trim domain family that contains a RING finger domain, B boxes, and an alpha helical coiled coil region. KAP-1 functions as a corepressor by interacting with the KRAB domain of KRAB zinc-finger transcriptional repressors. KAP-1 also appears to function as a scaffold for chromatin-remodeling complexes involved in transcriptional repression.

Immunogen Sequence:Synthetic peptide of human KAP-1

Target Alternative Name:KAP1, KRAB-associated protein 1; TF1B, TIF1B, TIF1-beta, transcriptional intermediary factor 1-beta; TRIM28: tripartite motif-containing 28; Nuclear corepressor KAP-1

Species Reactivities:Human

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Formulation:100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunoprecipitation

Positive Control:/

Application And Usages:Western blotting (1:500 – 1:2500) and immunoprecipitation. 293T cell lysate can be used as a positive control. However, the optimal concentrations should be determined individually. The antibody recognizes the KAP-1 of human origin. Reactivity to other species has not been tested.

Handling:The antibody solution should be gently mixed before use.